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Pharmacology (PHCL) Courses

Academic Unit: Pharmacology

PHCL 2001 - Basic Principles of Pharmacology: A Drug's Fantastic Voyage

(2 cr; Prereq-First-year chemistry Keywords: Pharmacology, Drug, Introduction, Pharmacogenetics, Addiction, Toxicity; Student Option; offered Every Fall)

Basic principles of pharmacology affecting drug from administration through action/elimination.

PHCL 3100 - Pharmacology for Pre-Med and Life Science Students

(2 cr; Prereq-College-level biology, biochemistry or physiology recommended; A-F or Audit; offered Every Spring)

Principles/mechanisms of drug action. Major drug categories for different organ systems.

PHCL 4001 - Mechanisms of Drug Action

(2 cr; Prereq-Upper div or instr consent; [prev or concurrent] courses in [biology, biochemistry] recommended; Student Option; offered Every Fall & Spring)

How drugs function as applied to the treatment of a single medical condition. Pharmacology, pharmacokinetics, pharmacodynamics, pharmacogenetics, pharmacogenomics.

PHCL 4003 - Anti-infective drugs: Drugs that kill invaders

(2 cr; Prereq-College-level biology; A-F or Audit; offered Every Spring)

Principles/mechanisms of anti-infective drugs, and treatments of infectious diseases.

PHCL 4010 - Current Research Topics in Pharmacology

(2 cr; Prereq-Upper div or instr consent; A-F only; offered Every Fall)

Cutting-edge research projects in pharmacology. Research seminars, literature studies, discussion sessions, oral presentations.

PHCL 4020 - Chemotherapy: from current anticancer drugs to future cancer therapeutics

(3 cr; Prereq-College-level biology: PHCL 2001 and/or PHCL3100, GCD4151 recommended.; A-F only; offered Every Fall)

This course will expose students to the studies of therapeutic agents used for the treatment of cancer. We will study the mechanisms of current anticancer drugs. We will also explore the recent development of novel anticancer agents, as well as the process of drug discovery & development.

PHCL 4100 - Laboratory in Molecular Pharmacology

(2 cr; Prereq-[2001 or 4001], 3100, [BioC 3021 or BioC 4331], [BioC 4025, BioC 4125 recommended]; A-F only; offered Every Fall & Spring)

Hands-on experimentation using molecular techniques for data collection/analysis.

PHCL 4343 - Pharmacology of the Synapse

(3 cr; A-F only; offered Every Fall)

Study synapse as pharmacological gateway to nervous system. Explore physiology of/cellular signalling at synapse, how signalling influences conditions such as Parkinson's disease, depression, anxiety, pain, addiction. How various drugs modify signalling at synapse. recommend: [PHCL 2001, PHCL 3100]

PHCL 4993 - Directed Studies (independent study)

(1 cr [max 3]; Prereq-instr consent, dept consent; S-N only; offered Every Fall, Spring & Summer; may be repeated for 6 credits; may be repeated 2 times)

Individual study ("dry lab" experience) on selected topics in pharmacology/biomedical science with faculty from the Pharmacology Department or other biomedicine disciplines. Readings and use of scientific literature.

PHCL 4994 - Directed Research (independent study)

(1 cr [max 3]; Prereq-instr consent, dept consent; S-N only; offered Every Fall, Spring & Summer; may be repeated for 12 credits; may be repeated 4 times)

Laboratory research ("wet lab" experience) in the areas of pharmacological/biomedical research.

PHCL 5108 - Introduction to Laboratory Research

(4 cr [max 5]; A-F only; offered Every Fall; may be repeated for 5 credits)

In this course, students will gain practical experience working in a biomedical research laboratory. Students will develop and refine skills required for productive and safe lab work. Topics covered in this class include lab safety, proper equipment usage, making solutions and related calculations, and fundamental concepts and techniques in molecular biology and signal transduction. Key course concepts and content will be reinforced by conducting experiments in the lab under the supervision of an experienced instructor.

PHCL 5109 - Introduction to Scientific Communication

(1 cr [max 18]; Prereq-student in the Graduate Program in Pharmacology (MS program) or approval from the Director of Graduate StudiesKeywords: Pharmacology, Directed, Independent Study, Biomedical, Basic Science, Research, Drug; Student Option; offered Every Fall, Spring & Summer; may be repeated for 18 credits)

This course is an interactive classroom experience focused on developing student communication skills. The primary emphasis is on student presentations of their research projects. In addition to making verbal presentations, students are expected to provide constructive criticism and feedback to their peers. Students also work on scientific writing skills by preparing a one-page NIH-style Specific Aims page outlining their research project.

PHCL 5110 - Introduction to Pharmacology

(3 cr; A-F or Audit; offered Every Fall)

This is a course for first-year students in the Graduate Program in Pharmacology. The course introduces students to the basic principles of pharmacology and focuses on molecular mechanisms of drug action. Topics covered include pharmacokinetics, pharmacodynamics, signal transduction, toxicology pharmacogenomics, and drug discovery. Prerequisites: student in the Graduate Program in Pharmacology or approval from the Course Director(s) Keywords: Introduction, Pharmacology, Molecular, Drug, Pharmacokinetics, Pharmacodynamics, Protein, Pharmacokinetics

PHCL 5111 - Pharmacogenomics

(3 cr; Prereq-Grad student or instr consent Keywords: Pharmacology, Pharmacogenomics, Toxicogenomics, Proteomics, Genetics, Drug; A-F or Audit; offered Every Spring)

Human genetic variation, its implications. Functional genomics, pharmacogenomics, toxicogenomics, proteomics. Interactive, discussion-based course.

PHCL 5112 - Foundations of Biomedical Research

(2 cr [max 4]; Prereq-student in the Graduate Program in PharmacologyKeywords: Basic Science, Pharmacology, Personnel, Writing, Presentation, Protein, DNA, Molecule, Microscope, Bioinformatics, Drug; A-F only; offered Every Fall; may be repeated for 4 credits)

This is a course for first-year students in the Graduate Program of Pharmacology. This course will introduce graduate students to the basic operating principles and techniques of a scientific research laboratory, general concepts surrounding experimental design and experimental controls, and familiarity with common laboratory calculations. Discussion of scientific techniques will include recombinant DNA and molecular biology techniques, protein expression and purification, protein assays, biochemical data analysis and fitting methods, transcriptomics and proteomics studies, and cell culture and mouse models of disease. Methods are presented in the context of highlighting general principles in experimental design.

PHCL 5115 - Neuropsychopharmacology

(3 cr; A-F only; offered Every Spring)

This course is designed to provide a comprehensive survey of neuropsychopharmacology with an emphasis on pharmacological principles. This course covers the study of brain chemistry in the context of health and disease. Students will be introduced to the neurobiological mechanisms of neurological and neuropsychiatric diseases and learn about the approved drugs and the investigational treatments for these disorders. This course provides an overview of drugs and biological interventions commonly used in clinical practice, their benefits and adverse effects, underlying brain mechanisms, and the research to support their effectiveness. Students will also be introduced to important research methods used in neuropsychopharmacology. Students will be expected to integrate this information and apply it to short answer and experimental design exam questions.

PHCL 5462 - Neuroscience Principles of Drug Abuse

(2 cr; Prereq-instr consent; Student Option; offered Periodic Spring)

Equivalent courses: was NSC 5462 until 06-SEP-05, was NSC 5462 until 18-JAN-05, was NSC 5462 until 19-AUG-02, NSC 5462

Current research on drugs of abuse, their mechanisms of action, characteristics shared by various agents, and neural systems affected by them. Offered biennially, spring semester of even-numbered years.

PHCL 5993 - Directed Studies

(1 cr [max 6]; Prereq-instr consent, dept consent max crs 6; 2 completions allowed; S-N only; offered Every Fall, Spring & Summer; may be repeated for 6 credits; may be repeated 2 times)

Individual study ("dry lab" experience) on selected topics in pharmacology/biomedical science with faculty from the Pharmacology Department or other biomedicine disciplines. Readings and use of scientific literature.

PHCL 5994 - Directed Research

(1 cr [max 12]; Prereq-instr consent, dept consent max crs 12; 4 completions allowed; S-N only; offered Every Fall, Spring & Summer; may be repeated for 48 credits; may be repeated 4 times)

Laboratory research ("wet lab" experience) in the areas of pharmacological/biomedical research.

PHCL 8014 - Small RNA Biology

(2 cr; Prereq-BIOC 8002 or MICA 8004 or equiv or instr consent; A-F or Audit; offered Every Spring)

Small RNAs as major regulators of gene/protein expression. MicroRNAs and their potential use in diagnosis/prognosis of various disease conditions, including cancers. Biology of small RNAs and their role in health and disease.

PHCL 8026 - Neuro-Immune Interactions

(3 cr; Prereq-MICA 8001 or equiv or instr consent; Student Option; offered Every Fall)

Regulatory systems (neuroendocrine, cytokine, autonomic nervous systems) linking brain/immune systems in brain-immune axis. Functional effects of bidirectional brain-immune regulation.

PHCL 8100 - Laboratory Research in Pharmacology (independent study)

(4 cr; Prereq-Grad student or instr consent Keywords: Pharmacology, Lab, Research, Data, Analysis, Benchwork, Hypothesis, Basic Science; S-N only; offered Every Fall & Spring; may be repeated for 8 credits; may be repeated 2 times)

Supervised independent research in pharmacology. Modern biomedical/pharmacology research methodology, data generation/analysis. Formulation/testing of basic science hypotheses.

PHCL 8200 - SciComm I: Critical Analysis & Publishing

(1 cr [max 2]; A-F only; offered Every Fall; may be repeated for 8 credits; may be repeated 8 times)

The mission of the course is to increase the students? ability to critically evaluate and comprehend the scientific literature, properly present scientific literature/figures, and critique presentations related to the field of pharmacology. After the course is completed, the students will be able to understand and differentiate the six components of a scientific paper, quickly identify the hypothesis and objective of a scientific paper, recognize the key figure(s), with controls, that support the hypothesis, how to present scientific data, how to submit journal articles and navigate the submission and publication process, and critique presentations. Prerequisites: student in the Graduate Program in Pharmacology Keywords: Pharmacology, Seminar, Presentation, Lecture, Research, Basic Science

PHCL 8208 - Neuropsychopharmacology

(3 cr; Prereq-[5212, Psy 5021, Psy 5061] or instr consent; A-F or Audit; offered Fall Even Year)

Relationships between drugs/biochemical, behavioral, neurophysiological consequences. Functional biogenic amine, peptidergic. How manipulations alter neuronal function or behavior. Feedback mechanisms, induction, inhibition. Reinforcement of, tolerance to, or dependence on drugs.

PHCL 8209 - Substance Abuse at the Bedside

(1 cr; Prereq-Grad student in any basic-science program; S-N only; offered Every Fall & Spring)

Clinical management of addictive diseases. Students discuss how observed clinical interactions can influence a basic science project in which they are involved.

PHCL 8211 - Advanced Pharmacology (Partially Online)

(5 cr; A-F only; offered Every Spring)

This hybrid course offers a combination of online and in-class lectures coupled with interactive literature discussion/flipped classroom components. The course has three sections focusing on 1) pharmacology of the autonomic, cardiovascular, and respiratory systems, 2) anti-cancer and anti-microbial therapeutics and 3) pharmacology of the nervous system. Course Instructors will highlight key features of currently utilized therapeutic agents and underscore recent advances in basic and clinical research that underpin emerging or potential approaches to pharmacotherapy. student in the Graduate Program in Pharmacology, or Course Director consent Keywords: Pharmacology, Drug, Therapy, Medical, Biomedical, Clinic

PHCL 8220 - The Ethical Scientist

(1 cr; S-N only; offered Every Spring)

This course focuses on scientific integrity in research and medicine. Topics to be discussed include best practices for experimental design, data collection, and analysis, regulatory requirements for human and animal studies, collaboration and authorship practices, and other social and ethical issues. Prerequisite: student in the Graduate Program in Pharmacology (GPP), or Course Director consent

PHCL 8221 - SciComm II: Writing & Research Presentation

(2 cr [max 3]; Prereq-student in the Graduate Program in Pharmacology (PhD program)Keywords: Pharmacology, Basic Science, Writing, Presentation, Practice, Thesis, Dissertation; A-F only; offered Every Fall; may be repeated for 3 credits)

Equivalent courses: was PHCL 5113 until 07-SEP-21

In collaboration with their mentors, students will develop thesis projects and scientific communication skills. Specifically, students will learn the principles of oral presentation, hone speaking style and slide content, and prepare for the departmental second-year talk. They will prepare sections of an NIH-style fellowship proposal in time for those eligible to submit an F31 NRSA application for the December deadline. This proposal will also comprise the written component of the preliminary exam. Students will also learn the elements of the closed-door component of the preliminary exam and how best to prepare. Throughout the class, students will provide feedback to their peers, develop critical thinking skills, and practice self-advocacy with their mentors, colleagues, and classmates in soliciting constructive criticism.

PHCL 8222 - Transdisciplinary Tobacco Research

(1 cr; Prereq-instr consent; S-N or Audit; offered Fall Odd Year; may be repeated for 2 credits; may be repeated 2 times)

Transdisciplinary science, its application to nicotine/tobacco research. Transdisciplinary theories/methods, examples of their application/integration. Draws on TTURC/local investigators, public health advocates. Offered every other year.

PHCL 8320 - Readings in Neurobiology

(1 cr [max 4]; Prereq-instr consent; Student Option; offered Every Fall & Spring; may be repeated for 4 credits; may be repeated 4 times)

Topics in neurobiology/neurophysiology.

PHCL 8333 - FTE: Master's

(1 cr; Prereq-Master's student, adviser and DGS consent; No Grade Associated; offered Every Fall, Spring & Summer; 6 academic progress units; 6 financial aid progress units)

(No description)

PHCL 8444 - FTE: Doctoral

(1 cr; Prereq-Doctoral student, adviser and DGS consent; No Grade Associated; offered Every Fall, Spring & Summer; 6 academic progress units; 6 financial aid progress units)

(No description)

PHCL 8555 - Master's Project

(5 cr; S-N only; offered Every Fall, Spring & Summer)

This course is intended to provide credit for the Plan B master's project that students on that track complete in the final semester of study. Only students who are enrolled in the MPaT master's Plan B track should register for this course. Learning objectives are tailored by the student's mentor and mentorship/examination committee. Benchmarks are assessed based on progress towards the project's completion, and the final grade is tied to the recommendation by the examination committee of the suitability of the project towards earning the terminal degree.

PHCL 8666 - Doctoral Pre-Thesis Credits

(1 cr [max 6]; Prereq-Doctoral student who has not passed prelim oral; no required consent for 1st/2nd registrations, up to 12 combined cr; dept consent for 3rd/4th registrations, up to 24 combined cr; doctoral student admitted before summer 2007 may register up to four times, up to 60 combined cr; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 12 credits; may be repeated 2 times)

TBD

PHCL 8777 - Thesis Credits: Master's

(1 cr [max 18]; Prereq-Max 18 cr per semester or summer; 10 cr total required [Plan A only]; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 50 credits; may be repeated 10 times)

(No description)

PHCL 8888 - Thesis Credit: Doctoral

(1 cr [max 24]; Prereq-Max 18 cr per semester or summer; 24 cr required; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 100 credits; may be repeated 10 times)

(No description)

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