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Oral Biology (OBIO) Courses

Academic Unit: Dent Diag & Bio Science Admin

OBIO 1 - Principles of Scientific Rigor and Reproducibility

(1 cr; Prereq-Graduate student in Oral Biology, Dental specialist, or instr consent; A-F or Audit; offered Every Spring)

This course explores topics surrounding rigor and reproducibility in research that are critical for success in obtaining funding and publications.

OBIO 5001 - Methods in Research and Writing

(2 cr; Student Option; offered Every Fall)

Skills necessary to begin a research project, including literature review, hypothesis formation, research design, and writing. Each student develops a research protocol.

OBIO 5010 - Molecular Virology

(1 cr; A-F or Audit; offered Every Fall)

This course provides graduate students and upper-level undergraduate students with a knowledge base for understanding the molecular aspects of replication strategies utilized in virus replication. Topics for the course will focus on the molecular aspects of virus replication for the major virus families (e.g., arenaviruses, bacteriophages, flaviviruses, herpesviruses, orthomyxoviruses, picornaviruses, and retroviruses) as well as virus evolution, structure, and taxonomy.

OBIO 5020 - Virus Pathogenesis and Host Interactions

(1 cr; A-F or Audit; offered Every Fall)

This course provides graduate students and upper-level undergraduate students with a knowledge base for understanding virus pathogenesis and host interactions. Topics for the course will focus on the molecular, cellular, and organismal aspects of virus pathogenesis and host interactions. The concepts of cellular pathogenesis, tissue tropism, portals of entry, local replication and virus spread, virus dissemination, and congenital infections will be covered. A particular emphasis will be placed on virus pathogenesis of the major virus families (e.g., arenaviruses, bacteriophages, flaviviruses, herpesviruses, orthomyxoviruses, picornaviruses, and retroviruses) and virus-host cell interactions that can restrict virus replication and are responsible for immunity will be discussed.

OBIO 5030 - Virology Research Presentations

(1 cr; S-N only; offered Every Fall & Spring; may be repeated for 10 credits; may be repeated 10 times)

Equivalent courses: was VIRO 5030 until 06-SEP-22

This course is designed to enhance knowledge in virology through research presentations as well as the critical evaluation of presentations of other students and researchers. Presentation will includes current virology research, both individual research projects and critical reading, and presentation of current literature.

OBIO 5050 - Evolution of Emerging Viruses

(2 cr; A-F or Audit; offered Every Spring)

This course is designed to provide graduate students and undergraduate students with junior or senior standing a knowledge base for understanding how HIV and other emerging viruses (e.g., Ebola, influenza, SARS, West Nile virus, hantavirus, hepatitis C) evolve and become public health threats. Topics for the course will focus on the biochemical, molecular, cellular, clinical, and epidemiological aspects of emerging viruses, with an emphasis on how each plays a role in virus evolution and emergence. This course will emphasize HIV as a key example of an emerging virus disease that has had a profound impact on human health.

OBIO 6500 - Research Topics in Oral Health & Biology

(3 cr; Prereq-Graduate student in Oral Biology, Dental specialist, or instr consent ; A-F or Audit; offered Every Fall)

This course introduces graduate students and dental residents to research areas in oral health and biology through faculty experts. Students learn to critically read and review research articles.

OBIO 8001 - Principles of Scientific Rigor and Reproducibility

(1 cr; Prereq-Graduate student in Oral Biology, Dental specialist, or instr consent; A-F or Audit; offered Every Spring)

This course explores topics surrounding rigor and reproducibility in research that are critical for success in obtaining funding and publications.

OBIO 8010 - Molecular Virology

(2 cr; A-F or Audit; offered Every Spring)

Equivalent courses: was VIRO 8010 until 15-MAY-23

This course provides graduate students with a knowledge base for understanding the molecular aspects of replication strategies utilized in virus replication. Topics for the course will focus on the molecular aspects of virus replication for the major virus families (e.g., arenaviruses, bacteriophages, flaviviruses, herpesviruses, orthomyxoviruses, picornaviruses, and retroviruses) as well as virus evolution, structure, and taxonomy.

OBIO 8012 - Basic Concepts in Skeletal Biology

(2 cr; A-F or Audit; offered Every Spring)

Cells (osteoblasts, osteoclasts, chrondrocytes) that make up skeleton. Transcription/signaling networks that regulate cell growth/differentiation. Mechanisms of bone remodeling. Regulation of bone by such agents such as hormones. Prereq Grad student or instr consent.

OBIO 8018 - Topics in Oral Pathobiology (Topics course)

(2 cr; Prereq-All students must be degree-seeking graduate students or dental fellows and should hold a PhD or DDS. instr consent for 4th year dental students and PhD students. CDE available for practitioners.; A-F or Audit; offered Every Fall; may be repeated for 4 credits; may be repeated 2 times)

Clinical understanding of oral disease. Correlates about underlying basic mechanisms in microbiology, immunology, cancer biology, developmental biology, neuroscience. Dialog between clinic/bench to improve preventative/treatment modalities.

OBIO 8020 - Virus Pathogenesis and Host Interactions

(2 cr; A-F or Audit; offered Every Spring)

This course provides graduate students with a knowledge base for understanding virus pathogenesis and host interactions. Topics for the course will focus on the molecular, cellular, and organismal aspects of virus pathogenesis and host interactions. The concepts of cellular pathogenesis, tissue tropism, portals of entry, local replication and virus spread, virus dissemination, and congenital infections will be covered. A particular emphasis will be placed on virus pathogenesis of the major virus families (e.g., arenaviruses, bacteriophages, flaviviruses, herpesviruses, orthomyxoviruses, picornaviruses, and retroviruses) and virus-host cell interactions that can restrict virus replication and are responsible for immunity will be discussed.

OBIO 8021 - Oral Microbiology

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; Student Option; offered Fall Odd Year)

Role of indigenous human oral microflora in health/disease. Colonization of oral cavity. Role of specific pathogens in development of dental caries and periodontal diseases. Infections of dental pulp and periapical tissues. Oral manifestations of viral/fungal infections. Microbial considerations in specialty areas of dental practice.

OBIO 8022 - Oral Neuroscience

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; Student Option; offered Spring Odd Year)

Background lectures and student presentations on current research topics to evaluate questions in general motor/sensory function related to oral/nasal structures. Taste, smell, and other chemical senses as they relate to those structures.

OBIO 8023 - Physical Biology of the Oral Cavity

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; A-F or Audit; offered Spring Even Year)

Structure/function of load-bearing components of human masticatory system from biophysical point of view. Mandibular form/movement. Infrastructure of hard tissues as related to occlusal wear and masticatory efficiency. Role of saliva and salivary pellicle in reduction of interocclusal friction. Computer simulation of jaw mechanics.

OBIO 8024 - Genetics and Human Disease

(1 cr; Prereq-Dental specialist or oral research trainee or instr consent; Student Option; offered Every Spring)

Principles of medical genetics. Emphasizes oral diseases. Twins, chromosomes, recombinant DNA, major gene traits, genes in populations, chromosomal abnormalities, complex traits, facial clefts, dental caries, periodontal diseases.

OBIO 8025 - Topics in Cariology

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; A-F or Audit; offered Spring Even Year)

Lectures, assigned readings, and discussions of basic epidemiological, biological, and chemical aspects of dental caries. Etiology, epidemiology, and pathogenesis of dental caries. Influence of dietary, salivary, plaque, and microbial factors on caries process.

OBIO 8026 - Salivary Glands and Secretions

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; A-F or Audit; offered Fall Even Year)

Salivary gland structure/development. Mechanisms/control of macromolecule/electrolyte secretion. Salivary protein structure/function, interactions with bacteria. Salivary pellicle, salivary gland disease. Clinical studies, readings, student presentations. Each student develops a research proposal.

OBIO 8027 - Biomaterials in Regenerative Dentistry

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; A-F or Audit; offered Fall Odd Year)

Describes most modern research strategies that are being developed by interdisciplinary groups to obtain revolutionary materials for its use in tissue engineering and regenerative medicine. The central role of biotechnology, nanotechnology, and biomimetics in these research strategies is highlighted. Focus on dental applications is provided.

OBIO 8028 - Molecular Basis of Cellular and Microbial Adhesion

(2 cr; Prereq-Dental specialist or oral research trainee or instr consent; A-F or Audit; offered Spring Odd Year)

Biochemical basis of adhesion phenomena. Cells of immune system, development of organs, tissue formation, bacterial colonization of the human.

OBIO 8030 - Oral Biology Seminar

(1 cr; Prereq-Dental specialist or oral research trainee or instr consent; S-N or Audit; offered Every Fall & Spring; may be repeated for 10 credits; may be repeated 10 times)

Faculty and student discussion of current topics in oral biology.

OBIO 8050 - Evolution of Emerging Viruses

(2 cr; A-F or Audit; offered Fall Odd Year)

This course is designed to provide PhD-level graduate students a knowledge base for understanding how HIV and other emerging viruses (e.g., Ebola, influenza, SARS, West Nile virus, hantavirus, hepatitis C) evolve and become public health threats. Topics for the course will focus on the biochemical, molecular, cellular, clinical, and epidemiological aspects of emerging viruses, with an emphasis on how each plays a role in virus evolution and emergence. This course will emphasize HIV as a key example of an emerging virus disease that has had a profound impact on human health. MS-level and advanced undergraduate students should register for OBIO 5050.

OBIO 8093 - Tutorial in Oral Biology

(1 cr [max 2]; Prereq-instr consent; S-N only; offered Every Fall & Spring; may be repeated for 2 credits)

Semester-long apprenticeship with faculty members to familiarize students with faculty research interests. Individual study of selected topics.

OBIO 8094 - Directed Research

(1 cr [max 10]; Prereq-instr consent; S-N or Audit; offered Every Fall & Spring; may be repeated for 10 credits)

tbd

OBIO 8333 - FTE: Master's

(1 cr; Prereq-Master's student, adviser and DGS consent; No Grade Associated; offered Every Fall, Spring & Summer; 6 academic progress units; 6 financial aid progress units)

(No description)

OBIO 8371 - Mucosal Immunobiology

(3 cr; Prereq-MICa 8001 or equiv or instr consent; A-F or Audit; offered Every Fall)

Equivalent courses: MICA 8371, CMB 8371

Host immune processes at body surfaces. Innate/adaptive immunity at mucosal surfaces. Interactions/responses of various mucosal tissues to pathogens. Approaches to target protective vaccination to mucosal tissues. Lectures, journal.

OBIO 8444 - FTE: Doctoral

(1 cr; Prereq-Doctoral student, adviser and DGS consent; No Grade Associated; offered Every Fall, Spring & Summer; 6 academic progress units; 6 financial aid progress units)

(No description)

OBIO 8666 - Doctoral Pre-Thesis Credits

(1 cr [max 6]; Prereq-Doctoral student who has not passed prelim oral; no required consent for 1st/2nd registrations, up to 12 combined cr; dept consent for 3rd/4th registrations, up to 24 combined cr; doctoral student admitted before summer 2007 may register up to four times, up to 60 combined cr; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 12 credits; may be repeated 2 times)

tbd

OBIO 8777 - Thesis Credits: Master's

(1 cr [max 18]; Prereq-Max 18 cr per semester or summer; 10 cr total required [Plan A only]; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 50 credits; may be repeated 10 times)

(No description)

OBIO 8888 - Thesis Credit: Doctoral

(1 cr [max 24]; Prereq-Max 18 cr per semester or summer; 24 cr required; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 100 credits; may be repeated 10 times)

(No description)

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