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Experimental and Clinical Phar (ECP) Courses

Academic Unit: Experimental & Clinical Pharm

ECP 5220 - Regulatory Issues in Drug Research
(2 cr; Prereq-ECP grad student or Pharm.D. professional student or instr consent; Student Option; offered Every Fall)
Regulatory issues encountered in conducting drug research trials. Performing different aspects of clinical trials. Lectures, readings, small group discussions, homework assignments.
ECP 5290 - Clinical Clerkship
(1 cr [max 8]; Prereq-Grad experimental and clinical pharmacology; Student Option; offered Every Fall; may be repeated for 16 credits; may be repeated 16 times)
Supervised study of pharmaceutical services at University of Minnesota Medical Center, Fairview or affiliated institutions.
ECP 5610 - Pharmacoepidemiology
(2 cr; Student Option)
Equivalent courses: was SAPH 5610 until 08-SEP-15
Application of epidemiologic principles to study use of and beneficial/adverse outcomes of drugs in human populations
ECP 5620 - Drug Metabolism and Disposition
(3 cr; Prereq-Grad student or instr consent; A-F or Audit; offered Spring Odd Year)
Oxidatative/conjugative enzymes systems involved in human drug metabolism/disposition. Various in vitro models used to evaluate drug metabolism or chemical entity, pros/cons of each. Factors involved in conducting in vivo studies. Components used to predict in vivo drug disposition from in vivo studies.
ECP 5982 - Inter-Institutional Journal Club in Translational Research
(1 cr; Student Option; offered Every Fall; may be repeated for 2 credits; may be repeated 2 times)
This course is structured as an inter-institutional journal club between universities of Minnesota, Pittsburgh, and Kentucky that is focused on translational research in clinical pharmacology. Articles will be discussed on topics such as precision medicine, pharmacokinetics, pharmacometrics, pharmacogenomics, and clinical biomarkers.
ECP 5983 - Scientific Communications in Experimental and Clinical Pharmacology
(1 cr; Student Option; offered Spring Odd Year)
Introduction of professional development concepts in written and oral scientific communication through lectures, literature readings, and class participation.
ECP 5984 - Scientific Communications in Experimental and Clinical Pharmacology II
(1 cr; Student Option; offered Spring Even Year)
Dissemination of advanced professional development concepts in written and oral scientific communication through lectures, literature readings, and class participation.
ECP 5993 - Directed Study in Experimental and Clinical Pharmacology
(1 cr [max 4]; Student Option; offered Every Fall & Spring; may be repeated for 8 credits; may be repeated 2 times)
Student working with faculty member designs a directed study course, including a complete syllabus, appropriate time commitment, and workload for number of credits.
ECP 5994 - Directed Research in Experimental and Clinical Pharmacology
(1 cr [max 4]; Student Option; offered Every Fall & Spring; may be repeated for 4 credits)
Student works with faculty adviser to design a scientific research project.
ECP 8100 - Seminar
(1 cr; Prereq-ECP grad student or instr consent; S-N only; offered Every Fall & Spring; may be repeated for 8 credits; may be repeated 8 times)
Selected topics in experimental/clinical pharmacology.
ECP 8200 - Research Problems
(1 cr [max 8]; Prereq-Grad SACP major (ECP Track) or instr consent; Student Option; offered Every Fall, Spring & Summer; may be repeated for 16 credits; may be repeated 16 times)
Individually designed research experience directed at contemporary problems related to drug use.
ECP 8210 - Clinical Therapeutics
(3 cr; Prereq-SACP grad major in ECP track or instr consent; Student Option; offered Periodic Fall)
Topics in clinical pharmacology that illustrate continuum of pathophysiology of a disease state, its contemporary treatment, problems or controversial issues with treatment approaches, strategies to advance therapy. Lectures, readings.
ECP 8220 - Experimental and Clinical Pharmacology
(3 cr; Prereq-SACP grad major (ECP track) or instr consent; Student Option; offered Every Fall)
Theory of advanced methodologies, applications, and evaluation techniques used to determine efficacy/toxicity of new drug therapies. Techniques for collecting/evaluating data.
ECP 8230 - Principles of Clinical Pharmacology
(2 cr; Prereq-Grad student in Experimental and Clinical Pharmacology or instr consent; A-F only; offered Every Fall)
Factors determining drug exposure, drug-receptor pharmacology, drug response. Personalized medicine including drug interactions, obesity, age (geriatrics/pediatrics), critical illness, therapeutic evaluation, drug development.
ECP 8290 - Clinical Clerkship
(2 cr; Prereq-Grad SACP major in ECP track or instr consent; Student Option; offered Periodic Fall & Spring)
Supervised study of pharmaceutical services at Fairview-University Medical Center or affiliated institutions.
ECP 8333 - FTE: Master's
(1 cr; No Grade Associated; offered Every Fall, Spring & Summer; 6 academic progress units; 6 financial aid progress units)
FTE: master's. Prereq-Master's student, adviser and DGS consent.
ECP 8444 - FTE: Doctoral
(1 cr; No Grade Associated; offered Every Fall, Spring & Summer; 6 academic progress units; 6 financial aid progress units)
FTE: doctoral. Prereq-Doctoral student, adviser and DGS consent.
ECP 8500 - Advances in Pharmacometrics Modeling and Simulation
(1 cr; Prereq-Grad student in ECP or PHM or instr consent; S-N only; offered Every Fall & Spring; may be repeated for 6 credits; may be repeated 6 times)
Equivalent courses: was ECP 8430 until 22-JAN-19
Modeling/simulation at interface between physiological/pharmacological processes. Current literature, discussion groups. Computer applications using relevant software programs.
ECP 8501 - Pharmacometrics
(2 cr; Prereq-ECP grad major or PHM grad major or instr consent; Student Option; offered Periodic Fall & Spring)
Equivalent courses: was ECP 8400 until 22-JAN-19
Theory/application of contemporary methods for analysis of concentration-time data and exposure-response relationships.
ECP 8502 - Introductory Population Pharmacokinetic Methods
(2 cr; Student Option; offered Periodic Fall, Spring & Summer)
Equivalent courses: was ECP 8410 until 22-JAN-19
Theoretical background for using mixed effects model in population analysis. Building fixed/random effects into a pharmacostatistical model. Project allows students to become familiar with a contemporary population pharmacokinetic analysis program.
ECP 8503 - Intermediate Population PK/PD Methods
(2 cr; A-F or Audit; offered Periodic Fall & Spring)
This course will present the theory and hands-on application of intermediate population methods using nonlinear mixed-effects model applied to pharmacologic systems.
ECP 8504 - Modeling Biologics
(2 cr; Prereq-A course in basic pharmacokinetics; enrollment in the Experimental & Clinical Pharmacology or Pharmaceutics graduate program, or instructor consent ; A-F only; offered Periodic Fall & Spring)
Equivalent courses: was ECP 8440 until 22-JAN-19
This course will develop computer skills to apply nonlinear regression models to describe the pharmacokinetics and pharmacodynamics of biologics.
ECP 8505 - Application of physiological-based pharmacokinetic modeling(PBPK) to model-informed drug development
(2 cr; A-F only; offered Periodic Fall & Spring)
Theory/implementation of contemporary methods for analysis and simulation of PBPK to support model-informed drug development.
ECP 8506 - Clinical Trial Simulation
(2 cr; Prereq-ECP grad or instr consent; Student Option; offered Every Spring)
Equivalent courses: was ECP 8420 until 22-JAN-19
Theory/application of contemporary methods of using simulations to design more efficient/informative clinical trials.
ECP 8666 - Doctoral Pre-Thesis Credits
(1 cr [max 6]; Prereq-Doctoral student who has not passed prelim oral; no required consent for 1st/2nd registrations, up to 12 combined cr; dept consent for 3rd/4th registrations, up to 24 combined cr; doctoral student admitted before summer 2007 may register up to four times, up to 60 combined cr; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 12 credits; may be repeated 2 times)
Doctoral pre-thesis credits.
ECP 8776 - Project Credits: Master's Plan B
(1 cr [max 18]; Prereq-Max 18 cr per semester or summer; 10 cr total required (Plan B only); No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 50 credits; may be repeated 10 times)
Project credits: master's Plan B
ECP 8777 - Thesis Credits: Master's
(1 cr [max 18]; Prereq-Max 18 cr per semester or summer; 10 cr total required [Plan A only]; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 50 credits; may be repeated 10 times)
Thesis credits: master's.
ECP 8888 - Thesis Credit: Doctoral
(1 cr [max 24]; Prereq-Max 18 cr per semester or summer; 24 cr required; No Grade Associated; offered Every Fall, Spring & Summer; may be repeated for 100 credits; may be repeated 10 times)
Thesis credit: doctoral.
ECP 8900 - Advanced Topics in Experimental and Clinical Pharmacology (Topics course)
(1 cr [max 4]; Prereq-ECP grad program or instr consent; Student Option; offered Every Fall & Spring; may be repeated for 8 credits; may be repeated 4 times)
Topic varies depending on faculty teaching course.
ECP 8940 - Advanced Topics: Regulatory Science and Affairs
(1 cr; Student Option; offered Every Fall & Spring; may be repeated for 4 credits; may be repeated 4 times)
This course will introduce students to the roles and responsibilities of key partners in ensuring regulatory compliance in a variety of settings. It will cover animal and human research as well as drug development. Speakers will delve into how research and development regulations are communicated, applied, and enforced in both academic Institutions and in Industry settings. The goal of this course is to provide an overview of how regulations shape key roles and enlighten students as to potential career paths in the field of regulatory science.
ECP 8982 - Inter-Institutional Journal Club in Translational Research
(1 cr; Student Option; offered Every Fall; may be repeated for 2 credits; may be repeated 2 times)
This course is structured as an inter-institutional journal club between universities of Minnesota, Pittsburgh, and Kentucky that is focused on translational research in clinical pharmacology. Articles will be discussed on topics such as precision medicine, pharmacokinetics, pharmacometrics, pharmacogenomics, and clinical biomarkers.
ECP 8983 - Scientific Communications in Experimental and Clinical Pharmacology
(1 cr; Student Option; offered Every Spring)
Introduction of professional development concepts in written and oral scientific communication through lectures, literature readings, and class participation.
ECP 8984 - Interpersonal Communications in Experimental and Clinical Pharmacology
(1 cr; A-F only; offered Spring Even Year)
The course emphasizes on developing basic skills for critical evaluation of scientific communication and provides opportunities for practicing these principles. The objectives of the course are to 1) Provide a systematic review of the principles and practice of the various modes and forms of scientific communication including scientific papers, technical reports, presentations, and proposal writing and 2) Identify the different objectives of these communication modes, and understand key steps and ingredients for effective scientific communication.
ECP 8992 - Directed Readings in Experimental and Clinical Pharmacology (Topics course)
(1 cr [max 2]; Student Option; offered Every Fall & Spring; may be repeated for 4 credits; may be repeated 4 times)
tbd
ECP 8993 - Directed Study in Experimental and Clinical Pharmacology
(1 cr [max 4]; Student Option; offered Every Fall & Spring; may be repeated for 4 credits; may be repeated 2 times)
ECP 8994 - Directed Research in Experimental and Clinical Pharmacology
(1 cr [max 4]; Prereq-[Grad ECP, adviser, DGS] consent; Student Option; offered Every Fall, Spring & Summer; may be repeated for 8 credits; may be repeated 2 times)
Directed research in experimental and clinical pharmacology.

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