Thin-film technology underlies many of today's products, ranging from magnetic recording discs to the familiar aluminized plastic foils used extensively in food packaging. Historically, thin films have been grown by chemical vapor deposition (CVD) or physical vapor deposition (PVD). MicroCoating Technologies, Inc. (MCT) has developed a novel Combustion Chemical Vapor Deposition (CCVD) process for production of nanostructured thin films and nanopowders. The process involves controlled thermal decomposition of one or more precursors in an atmospheric-pressure flame. It takes advantage of the capabilities of MCT's proprietary atomizer (the Nanomiser device), an innovative device that can produce a uniform spray of submicron-sized droplets having a narrow size distribution. This ultra-fine atomization enables the use of a wide range of precursors without concern for their vapor pressure; instead, the only requirement is for the precursors to be soluble in the chosen solvent system. Recently, MCT has begun an effort to expand the use of the Nanomiser device beyond materials synthesis to combustion applications in SI engines and gas turbines. In this talk, we will provide examples from recent development efforts that used MCT's Nanomiser device for aerosol materials synthesis and spray combustion applications.